Medicine

The article presents results of studies of chrysotile asbestos and health conducted by the Russian Academy of Medical Sciences (RAMS) Institute of Occupational Health, a brief review of foreign studies, the list of protective measures in the use of asbestos and other fibrous materials ensuring their controlled use.
2012

One of the most relevant, important and controversial problems of public life, politics and morality is abortion. The abortion and leading position in the structure of reproductive losses and the health of women of childbearing age is medico-social and contested issue in nowadays. Abortion as a whole remains the traditional method of regulation of reproductive behavior. Artificial abruption of life is a fundamental problem of human being, increasing interest in the article. This paper examines the effects that significantly impairs the reproductive system and serious complications for women's reproductive function after abortion, including maternal mortality. Showing prevention and solutions.
2012

In this article the main feature of action on people of carcinogenic agents is considered. This agents consist in large number of sources of their entry in environment and an organism of people, and complex combination of various factors. It creates certain difficulties on the track of a solution to the problem. The heavy metals is played a significant part of environmental pollution. The understanding of processes of migration and transition of elements from one environment in another has great practical value for studying of mechanisms and ways of impact on a human body and estimation of level of toxicity of chemical elements.
2013

In this article, we will introduce and discuss new options by using personal decision support and e-health services in diabetes management. Usage of the KADIS® system for personal decision support provides opportunities to identify improved therapy options in accordance with the guidelines of the professional societies. This enables the best treatment modality for the individual patient to be determined in a very short time and, individual circumstances of the patient as well as the practical feasibility of treatment recommendations are taken into account. Furthermore, the telemedicine platform TeleDIAB® together with the  embedded KADIS® simulation are suitable to make knowledge and experience globally available to treat diabetes.
2013

Authors showed that concentration around capillaries wall of complex Zn+2-chelator formed in result of inter­action in cytoplasm of B-cells of Zn+2-ions with diabetogenic zincbinding chelators is one of causes of devel­oped vascular changes in capillaries of pancreatic islets. These changes as alteration of basal membrane of capillaries, edema of endothelium, partial destruction of capillaries wall and hyperemia can to aggravate de­veloping of degenerative changes in pancreatic islets induced by Zn+2-chelator that result aggravation devel­oping of diabetes. Meanwhile main cause of developing of diabetes induced by zincbinding chelators is its ability to form toxic complexes with Zn+2-ions in B-cells that result necrosis and destruction of B-cells within short time.
2014

There was conducted investigation of the nephritic blood circulations in different levels of the nephritic arteries of 90 patients with the 2nd type of diabetes in combination with the chronic pyelo-nephritis in the phase of exacerbation and remission. There was determined disorder of the nephritic blood circulations in the form of the nephritic blood flow velocity lowering and the increasing of the nephritic vascular resistance in different levels of the nephritic arteries, the expressiveness of which is determined by the activity of the inflammatory process in kidneys.
2015

We have investigated 20 patients with type 2 diabetes, with an average age of 58,0 ± 4,32 years, with disease duration of 6,29 ± 1,28 years. The carbohydrate metabolism was estimated: fasting blood glucose and 2 hours later after meal, glycosylated hemoglobin (HbA1C). For the purpose of determine the safety of insulin analogues, have been studied biochemical parameters of blood before and after 3 months of therapy. The basic criterion of the safety of the therapy within 3 months of application study of insulin analogues was the number of daytime and nighttime hypoglycaemia, as well as the dynamics of body weight during the study period. Structural and functional state of the left parts of heart was assessed by echocardiography and dopplerography of transmitral blood flow.  For all  patients were assigned  insulin  analogues,  the average daily dose  was 32,4 ± 2,8 units, particularly rapid-acting insulin aspart (Novorapid) and acting insulin detemir (Levemir). Analogs of human insulin had a favorable effect on carbohydrate metabolism and reduced the incidence of nocturnal hypoglycemia. Also, there was a trend to improvement of the structural parameters and left ventricular diastolic function in patients with type 2 diabetes after treatment with insulin analogues. Application of insulin analogues have proven the safety of the insulin group in terms of prevention of hypoglycemia, which has a positive effect on cardiovascular events in the outcome of the treatment of diabetes. 
2015

Purpose of the research — to study the frequency of occurrence of polymorphism ST gene methylenetetra- hydrofolate patients with diabetes mellitus type 2 and its correlation with homocysteine levels and the devel- opment of ischemic heart diseases. 118 patients with diabetes mellitus type 2 at the age of 45–60 years were surveyed. Statistically significant differences were observed frequencies of alleles of T and S, genotype SS between groups of patients with pancreatic diabetes type 2 with ischemic heart disease and tran- sferred myo- cardial infarction and healthy persons. It was found that the allele T 677 gene, methylentetrahydrofolat- reductase associated with an increased risk of myocardial infarction in patients with diabetes mellitus type 2 (OR=1,879, p=0,029). The combination of genotype T677 gene methylenetetrahydrofolatereductase with hyperhomocysteinemia in 2 type diabetic patients with coronary heart disease is related with other risk factors for cardiovascular diseases and can have a significant impact on the course of ischemic heart disease.
2015

It is showed by authors that using of 8-para(toluenesulphonylamino)quinoline — a derivative of 8-oxyquinolin result histochemical revealing by using of fluorescent microscopy of Zn+2-ions in cells of tissue of prostate, in pancreatic B-cells and in salivary glands contains a large amounts of ions.
2015

This paper summarizes results of clinical studies in the period of years 1971–2014 as follows: (1) In persons with type 1 diabetes, effectiveness of conventional therapy with multiple doses of shortacting insulin (MDI) or continuous sucutaneous insulin infusion (CSII) was demonstrated. Dynamic training was shown to enhance insulin sensitivity and plasma HDL cholesterol, and to improve neuropathy, memory and attention. Influence of alcohol and effects of insulin on postprandial alcohol concentrations revealed similar consequences; model experiments were suggested when answering forensic questions. (2) In persons with type 2 diabetes, advantage of complementary therapy with prandial rapid acting insulin was demonstrated. In MDIpersistent hyperglycaemia, insulin pump was shown to reduce HbA1c, to diminish daily insulin dose and to improve quality of life. Benefits of incretin preparations were described. Effects of losartan on renal and cardiovascular outcomes in diabetic nephropathy were documented. (3) Perinatal mortality of newborns of mothers with diabetes decreased due to thorough diabetes and obstetric care. (4) Manual Device for Insulin injections (MADI-pen) was developed and introduced into daily routine. Its accuracy, pharmacological and microbial safety were proved. (5) «Programmed Treatment of persons with diabetes» comprising the principels of Therapeutic Patients Education of the WHO was introduced. (6) Glycaemic Index of foods was calculated using a new method with continuous glucose monitoring. (7) Intensive selfmonitoring. The accuracy and precision of various glucometers were explored. Tenpoint ambulatory glycaemic profile and continuous glucose monitoring system (CGMS) was introduced to practice. In persons on insulin pumps CGMS resulted in reduction of HBA1c.
2015

The article analyzes the literary publications devoted to the research in recent years. The nature and level of accumulation of metals in various biological fluids of man reflects the degree of pollution in the natural anomalous geochemical provinces, and allows us to study human impacts. The situation which has developed in Kazakhstan, complex multifactorial causes environmental effects on public health, which creates the need to carry out actions aimed at the adoption of specific solutions to control the state of heavy metals in the environment in the «habitat — a man.» According to the literature, there is a relationship between the accumulation of metals in the environment and their accumulation in the human biological fluids.
2015

This article contains information about the impact of mobile communicationson the human body. And also it considers the harmful of mobile phones to the human health. It is clear that electromagnetic radiation from mobile phones has a negative impact on the physiological state and psyche of the person. Not following the rulesof using of mobile phones are doing a lot of damage to the health of people.
2016

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