Marketing researches of pharmaceutical market in kazakhstan of antiparasitic medicines in veterinary

The general information about registratedantiparasitic medicines in the register of Agricultural Ministry of Republic of Kazakhstan were given in this article. Also apart from domestic productions, there are represented using percentage of foreign products and their leading countries and pharmaceutical organisations,which are placed the more space.As a result of researches, antiparasitic drugs in veterinary make 2,5% from general capacity. It is – 33,33% domestic products, and 66,66% foreign products. It means the most part consists of foreign medicines. 

Nowadays, due to the increase in the number of pediculous diseases among the animals, the demand for these medicines is still growing. At the same time, the most important problem is the development of optimal production of domestic products, as the products of other states take a significant part of the market. Parasitic (invasive) disease - a large group of animal and human illness who are caused by the pathogens of the animal origins[1]. Parasitic animal diseases are widespread in the territory of the Republic of Kazakhstan and cause significant economic damage, because animal health is a necessary condition for increasing livestock sustainability. Animal products are not only a source of high quality food, but also a source of income for many small farmers and livestock farmers in developing countries. Economic growth is accompanied by an increase in the consumption of animal products. In many developing countries livestock makes a significant contribution to agriculturalVVP.

There are published data on the using against invasive diseases, anthelmintic preparations have been used: santonine, hexochloroethane, sodium florified salt, piperazine, and others. The using of medicinal plants having an antihelmintic effect on this disease has not been studied. In recent years, the antihelmintic efficacy of some medicinal plants and their mixtures with chemical preparations against helminthiases has been studied. Recommendations were prepared on the use of these drugs in practice. Studies have shown the need to study the effectiveness of antihelminthic medicinal plants against helminthiases [2].

Considering the wide spread of helminthiases, which are most often found in the form of a mixed invasion, and for the treatment of the sustainable implementation of therapeutic and preventive measures in animal husbandry, highly effective domestic anthelmintic and other drugs, produced in significant amounts and at affordable prices are needed.

Traditional methods of fight against parasitic diseases of animals by use of chemotherapeutic medicines (anthelminthic) lose popularity because of development in resistance helminths to them and possible hit of residual amounts of chemical medicines in production of livestock production. The most effective remedies on fight against helminthoses are extracts of plants - natural enemies of helminths and other ecological receptions [3]. The purpose of our research is the analysis of the market of the medicines used in the veterinary area in the Republic of Kazakhstan.

Objectives:

• To consider the edition of countries-producers
• To define the dynamics of registered medicines from 2012 to 2016
• To compare the market value of the most demanded medicines
• To identify the percentage of dosage forms

Analysing materials. The state register of veterinary medicines and feed additives of the Republic of Kazakhstan, the Law of the Republic of Kazakhstan "About veterinary science".

Analysing methods.Marketing and graphic analyses, monitoring.

Results. As a result of the researches conducted by us it is defined that the proportion of domestic manufacturers consists 33,33%, foreign producers - 66,66% of the market of antiparasitic medicines for veterinary use (Picture 1).

Apparently from the Picture 1 domestic manufacturers release 13 (33,33%) medicines for invasive diseases. Foreign producers are issued 26 (66,66%) antiparasitic medicines for veterinary application.

Domestic manufacturers of invasive diseases (33,33%) treat of veterinary medicines:LLP «Agrobiotechvetservice» , LLP «BO- NА», LLP «Epsilon», LLP «Scientifical Manufactural centreBioVet», LLP «Microhim», LLP «Parytet», LLP «Kazpharmakom» ЖШС, LLP «ChemprojectDemeu-2070».

Table 1 - Foreign and domestic manufacturers from market percentages more than 5%

As appears from data of table 1, the market of antiparasitic medicines for veterinary use is presented by goods of 5

manufacturing countries. Leaders in the offer of medicinal There are several medicines registered in the govermental preparations of this group are: Kazakhstan - 33,33%, Russia - register of veterinary medicines and feed additives of the 20,51%, Ukraine - 7,69%. Republic of Kazakhstan (Official exit - 30.10.2017), which are represented in the Picture 2.

And also there is showed the market value of several medicines in the table - 2.

Table 2 -Market value of medicines

There are 4 different dosage forms of antiparasitic medicines registered in the governmental register of RK (Picture-3).

According to the Picture 3 it is visible that the most common dosage form is the solid dosage form - powder (50%) as has a number of advantages:

1. increase in therapeutic effect and biological availability
2. medicinal substances are easily and precisely dosed
3. it is convenient to receive various mixes
4. technology of powders fast and simple
5. big stability at storage in comparison with liquid forms
6. convenient transportation[6].

The least common dosage form is the aerosol (8%) [4].

Drawbacks:

1. rather high cost
2. a possibility of explosion of a cylinder at blow or action of high temperature
3. air pollution of the room medicines and propellants at manipulations[6].

Conclusion:

By results of a research it is possible to make a conclusion that the proportion of domestic manufacturers in the pharmaceutical market of Kazakhstan of antiparasitic medicinal preparations in a veterinary medicine is necessary only 33,33%, in comparison with foreign producers - 66,66%. From this it follows that it is necessary to increase local production as dynamic development of the pharmaceutical market is defined by its life priority. The pharmaceutical market represents the important sector of economy of any country and is index of its economic and social development, welfare of the population. The developed pharmaceutical industry of the country is considered an indicator of high innovation of its economy. Due to the constant increase in production and an aggravation of symptoms of the environment the increasing scale is assumed by a problem of evolution of diseases and their effective treatment. One of the priority directions of search of new sources of medicines is studying of flora of Kazakhstan which stocks are rather big. Such approach will provide a long-term reliable source of raw materials, will allow to use rationally these vegetable resources and will give the chance to dilate the range of medicinal vegetable raw materials and medicines on their basis.

REFERENCES

1. Tolkach N.G.. Veterinary pharmacology // The manual under edition of Tolkach N.G., A.I.Iatusevich. - Minsk: Technoperspectiva, 2007. - Р. 446-451.
2. DjafarovR.M. The efficiency of klozantet, invermectyn and albendzole at unascaridosis of calfs // Veterinary medicine. - 2009. - №4. - Р. 25-28.
3. D. Salkova, M. Panayotova-Pencheva, S. Movsesyan, Be'er S., Voronin M., Arkhipov I. Alternative methods for control of parasitic diseases in animals // Russian parasitic journal. - 2014. - №1. - Р 93-103.
4. Thegovermental register of veterinary medicines and feed additives of the Republic of Kazakhstan [Electronic resource] // MVH RK Committee of veterinary control and supervision. - Electronic data. - Access mode: http://mgov.kz/ napravleniya- razvitiya/veterinarnaya-bezopasnost
5. Law about veterinary of Republic of Kazakhstan from July 10, 2002 №339-O (with changes and additions for a state to 17.11.2015)
6. CH.I.Tichonov, A.I.Tichonov, T.G.Iarnych. Technology of medicines. Textbook Technology of medicines. - Publishing house NFAU, Zolotyestranyci, 2002. - 704 p.