Objectives of the study
Retrospective examinations of patients which were treated for colorectal cancer among the population of Turkestan (SK) region. According to their: ethnic; sexual; age differences; the location; the stage of tumor growth.
Materials and methods of the work
As the main core of the work were taken patients who are registered in the oncology center of the Turkestan region in 2012-2016. The total number of patients, the stage of tumor development, the level of total mortality for the year, 5-year viability were taken into account. In addition, the case histories of 261 patients were studied.
According to the case histories of the disease, the patients were divided into ethnic groups "Kazakhs", "Slavs", "Uzbeks" and "others".
Depending on the localization of tumors in the colon it was classified into: the right part of the colon (ceacum and ascending parts), the transverse part of the colon (from the hepatic angle to the splenic angle), the left part of the colon (descending part and sigmoid colon) and the rectum (rectosigmoid part, rectum).
Results of the study:
According to the stage of tumor growth the number of detected patients in the initial I–II stages of tumor development increased from 9 people in 2012 to 51 by 2016. This is a very good indicator.
The overall mortality rate for colorectal cancer has also been significantly increased. In 2012, the overall mortality rate was 30 patients, in 2016 - 51. For the retrospective analysis were selected 261 patients with colorectal cancer, 123 were male and 138 female, and the average age was 59.97 (among 23-83 year old patients) year.
As for the total number of patients registered for colorectal cancer, it was found out that the number of patients is increasing every year. If in 2012, 298 patients were registered, in 2016 this figure reached 356 people, that is, the growth increased by 58 people. The indicator of the column of 5-year survival of patients in the general calculation increased from 140 to 144, respectively. It shows that it is in a positive trend, though slightly.
According to the classification of ethnic groups it is obvious that the correlation deviations between the ethnic groups of the surveyed are also significant. This deviation may be due to the genetic predisposition of patients, peculiarities of nutrition (abundant animal fat in food, especially pork) and the indifference order of treatment to the doctor. Most often the tumor is located in the rectum (57.9%), the least in the transversal part (6.5%). The most frequent stage of development at the initial detection is the 3rd (49%), while the lowest is the 1st (3.4%) stage.
Slavs are more common to have a CRC.
CRC in Turkestan region is more common among women than men, but does not have much statistical significance, such as in European countries (Norway, Sweden, Denmark).
The average age of patients with colorectal cancer was 59.97 year. More than 60 % of registered patients are between 50 and 70 years.
Most often the tumor is located in the rectum (57.9%), the least in the transversal part (6.5%).
The most frequent stage of development at the initial detection is the 3rd (49%), while the lowest is the 1st (3.4%) stage.
the main reason for the frequent detection of the disease in the late stages (III-IV) shows that the program carried out for early detection is not more effective and that the indigenous population is indifferent to the disease.