Relevance. Psoriasis in all its clinical forms is the most common chronic skin disease. According to the International Federation of psoriasis prevalence in the world is about 3%[1,2]. Policausal, the high prevalence and the difficulty of treating psoriasis determine urgency of the fight against this disease [3].
Epidemiological, clinical and social importance of psoriasis in the present conditions cannot be overestimated. Psoriasis in all its various clinical forms is one of the most common chronic inflammatory skin diseases. For most patients, the disease is long-standing restrictions on the various aspects of everyday life with great personal cost, sometimes with severe stigma and discrimination.
Objective.To establish the relationship between the levels of incidence of psoriasis and the patient's lifestyle.
Objectives:
1. Examine the way of life in patients with psoriasis.
2. To study the incidence of psoriasis in the industrial metropolis.
Material and methods. We observed 315 patients with psoriasis, including 109 women and 196 men. In the study sample consisted of patients aged 18-65 years. The study did not include patients with psychoactive addiction or severe laboratory abnormalities.
All patients provided written informed consent to participate in research.To assess the combined effect of environmental factors used approach, which is based on comparison of the district average performance of its individual factors with relevant regional average figures, taken as a standard (reference).
Results and discussion. It was found that the prevalence of psoriasis in the city was 269.1 cases of 100 thousand. In the course of severity of psoriasis is most influenced by: the unfavorable family environment; the presence of harmful factors of production and the experience of working with them for more than 5 years; start drinking and smoking initiation before the age of 18 years; mental strain and stress.
The majority of patients discharged after hospital treatment with the residual effects. They are characterized by low physical and social activity associated with the skin condition and the common symptoms of the disease.
The most significant relative risk of transition from the group with mild disease in the group with moderate form, with increasing values include the patient's age, marital status, social group. Ranking indicators the most important values of the relative risks of the transition from the group with moderate form of the disease in the group with severe with increasing values were as follows: smoking more than a pack of cigarettes a day, early use (under 18) alcoholic beverages, nervous and mental stress at work and the low average income of a family of the patient [4].
The debut of psoriasis is most common between the ages of 26 to 40 years (43.1%). As triggered were psycho-emotional overstrains and stress (60.5%), hypothermia and colds (17.8%), receiving medicinal products (5.1%), alcohol (5.7%), physical injuries (5.1 %)[5,6].
The greatest proportion of patients who have bad habits, living in environmentally disadvantaged areas of the metropolis.The highest prevalence of psoriasis in Zaporizhia region registered in the city of Zaporozhye, Gulyai-Pole, Veselovsky, Kuibyshev, Primorsky and Vasilevsky areas. In these administrative units of the prevalence of psoriasis it is in the range 269.6 - 513.8 cl / 100 thousand.
Conclusions:
- Psoriasis is a disease with a multifactorial etiology. Genetic factors and environmental influences carry the cumulative impact on the pathogenesis of the disease.
- The main trigger factors include infectious and parasitic diseases, stress and psychosomatic factors, bad habits and poor diet, intake of drugs, metabolic disorders.
- Alcohol intoxication and smoking increase the risk of psoriasis contribute to the generalization of the process and the emergence of complicated forms; shorten the period of remission and limited treatment options.
- In order to achieve sustained remission in patients with psoriasis is required to carry out the correction of exogenous and endogenous trigger factors in order to minimize their impact.
- Materials socio-hygienic monitoring the incidence of psoriasis Zaporozhye region should be used to develop management solutions for the protection of air and water pollution from anthropogenic
Literature
- Belyaev EN Socio-hygienic monitoring in the solution of strategic tasks of habitat and population health / EN Belyaev, VI Chiburaev, MV Fokin // Hygiene and sanitation. 2002. - №3. - S. 9-12.
- VahitovSh.M. Family Medicine: marketing approach: Monograph / S. M. Vahitov, VA Gaponenko // Kazan, state. honey. Univ seemed mountains. cardiology. Dispensary. Kazan: Medicine, 2006 - 76 ..
- Galiullin AN Methodological and organizational bases of medical and social prevention: fav. Essays / ANGaliullin. Kazan: b. and., 2004.- 110c.
- Histological and immunohistochemical changes in the skin of patients with psoriasis; in the treatment of PUVA bath / VA Volnukhin et al. // Journal of Dermatology and Venereology. 2007. - №2. - P. 3-7.
- Grinhalh T. Evidence-based medicine: Per. from English. / T. Grinhalh; ed. AG Chuchalina. - 2nd ed. M., 2007. - 240 p.
- Gubler EV Computational methods of analysis and detection of pathological processes / EV Gubler.M .: Medicine, 1978. - 296 p.